Table 2:  Commercially Available Prophylactic Vaccines for HPV

Vaccine Indications Schedule Adverse Effects
Quadrivalent (HPV 6/11/16/18, Gardasil, Merck, Whitehouse Station, New Jersey) Should be routinely offered to all females 11-12 years old

 

Can vaccinate as young as 9 years old, and as old as 26 years old if not previously vaccinated

 

Boys and men 9-26 years old can also be vaccinated
Three doses at time 0, month 2 and month 6

 

 

Minimal

 

Mild to moderate localized pain, erythema, swelling

 

Systemic reactions, mainly fever, seen in 4% of recipients
Bivalent (HPV 6/11, Cervarix, GlaxoSmithKline, Rixensart, Belgium) Should be routinely offered to all females 11-12 years old

 

Can vaccinate as young as 9 years old, and as old as 26 years old if not previously vaccinated
Three doses at time 0, month 1 and month 6 Minimal

 

Mild to moderate localized pain, erythema, swelling